L-Methylfolate

Methylation controls multiple biochemical pathways in your body.

Your genetics, heart health, hormones, sleep, stress, mood, and detoxification depend on healthy methylation.

Where does your body get the methyl groups needed to carry out methylation? Primarily from folates that come from food and intestinal microbes. Food folates must be first converted into an active form before your body can use them.

Your MTHFR enzyme converts food folates into the active form of folate, methylfolate. This bioavailable form is also known as L-methylfolate. The true biochemical name is L-5-methyltetrahydrofolate (L-5-MTHF).^†

Over 50 percent of the population is thought to have a genetic mutation in their MTHFR gene. Thus, they may not be achieving adequate methylfolate levels from food alone.

Because L-5-MTHF bypasses the MTHFR enzyme, it can provide methylation support for those with MTHFR polymorphisms.^†

Folate (as bioavailable L-methylfolate) is:^†

• Easily absorbed and used by cells
• The predominant form of folate in circulation
• The only form of folate that can cross the blood-brain barrier
• Essential for methylation, DNA expression, homocysteine metabolism, and nervous system function

Seeking Health’s L-methylfolate contains 1,700 mcg DFE of methylfolate in the bioavailable form of L-5-methyltetrahydrofolate (L-5-MTHF).^†

The bioactive form of L-methylfolate (L-5-MTHF) is well-utilized in the methylation cycle. It is often the preferred form for those with methylation, homocysteine, or MTHFR gene mutation concerns.^†

Mutations in your MTHFR gene can lead to reduced L-methylfolate production and a less functional methylation cycle. Challenges in the methylation cycle are associated with an increased risk for cardiovascular and mood issues, birth defects, and infertility concerns.

Mutations in this gene can also slow your body’s ability to convert folate into its active forms. Thus, a large majority of people may benefit from consuming an L-methylfolate dietary supplement.^†

The most direct way to support methylation and MTHFR genetic mutations is with L-methylfolate (L-5-MTHF).^†

Supplementing with bioavailable L-methylfolate supports:^†

• Healthy methylation
• Positive mood
• Healthy homocysteine levels
• Nervous system function and development
• Prevention of neural tube defects during pregnancy
• Healthy energy production
• Normal cognitive, memory, and brain function

Get ready for your methylation cycle to fire on all cylinders with Seeking Health’s L-methylfolate!^†

Key Ingredients In L-Methylfolate